"Metilotru00f3ficas recombinant yeast strain producing a precursor of insulin, constructions of DNA and method for the production of CEPA.Metilotru00f3ficas recombinant yeast strain producing a precursor of insulin, DNA constructs and method to obtain the strain.The strain comprises in its genome at least one copy of a first construction of DNA and a second structure of DNA.Where these constructions of DNA are able to direct expression and release by means of a human insulin precursor of formula: B (1-30) - y1y2 - (1 - 21).Where Y1 is lysine or arginine; Y2 is lysine or arginine; B (1-30) is the peptide B of human insulin; and (1 - 21) is the peptide of human insulin and where the yeast strain is a strain of lightHard of Pichia pastoris.
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