Compound, pharmaceutical composition and methods to inhibit tyrosine kinase activity and cell proliferation, differentiation and / or mediator release in a patient suffering from a disorder, to treat a pathology linked to a hyperproliferative disorder, restenosis in a patient, and inflammation in a patient suffering from this disorder

摘要

"COMPOUND, PHARMACEUTICAL COMPOSITION AND METHODS TO INHIBIT THYROSINE KINASE ACTIVITY AND CELL PROLIFERATION, DIFFERENTIATION AND / OR MEDIATOR RELEASE IN A PATIENT SUFFERING A DISORDER, TO TREAT A HISTORICAL PATHOLOGY, A HISTORICAL PATHOLOGY IN A PATIENT SUFFERING FROM THIS DISTURBANCE ". This invention is directed to quinoline / quinoxaline compounds of formula (I) which inhibit platelet-derived growth factor or tyrosine kinase activity p56 ^ lck ^ to pharmaceutical compositions comprising these compounds, and to the use of these compounds for the treatment of a patient suffering from or subjected to disorders / conditions involving cell differentiation, proliferation, extracellular matrix production or mediator release and / or T cell activation and proliferation