首页> 外国专利> Compounds derived from 3 - (pyrrole or imidazole - il - 2 - 5 - il) methylene - 4.5 - pirazinoxindoles replaced inhibitors or modulators of the Protein Kinases (JNK), its Salts,Intermediates and Pharmaceutical compositions useful in the Treatment or control of inflammatory diseases such as rheumatoid arthritis.

Compounds derived from 3 - (pyrrole or imidazole - il - 2 - 5 - il) methylene - 4.5 - pirazinoxindoles replaced inhibitors or modulators of the Protein Kinases (JNK), its Salts,Intermediates and Pharmaceutical compositions useful in the Treatment or control of inflammatory diseases such as rheumatoid arthritis.

机译:衍生自3-[(吡咯或咪唑-il-2-5-il)亚甲基]-4.5-吡嗪诺辛酯替代的蛋白激酶(JNK),其盐,中间体和药物组合物的抑制剂或调节剂,可用于治疗或控制类风湿关节炎等炎症性疾病。

摘要

Compounds of formula I which correspond to compounds derived from 3 - (pyrrole or imidazole - il - 2 - 5 - il) methylene) - 4.5 - pirazinoxidoles replacedInhibitors of Protein Kinases (JNK), its Salts and Pharmaceutical compositions.Useful in the Treatment or control of inflammatory diseases such as rheumatoid arthritis, Neurodegenerative Diseases, or for the treatment of Solid tumors.Tumours such as Breast or Colon.
机译:对应于衍生自3--(吡咯或咪唑-il-2-5-il)亚甲基)-4.5-吡嗪二氧化物取代的式I的化合物蛋白质激酶抑制剂(JNK),其盐和药物组合物。控制炎症性疾病,例如类风湿性关节炎,神经退行性疾病或治疗实体瘤。肿瘤,例如乳房或结肠。

著录项

  • 公开/公告号CL1999003009A1

    专利类型

  • 公开/公告日2001-11-27

    原文格式PDF

  • 申请/专利权人 F. HOFFMAN-LA ROCHE AG;

    申请/专利号CL1999003009

  • 发明设计人 LUK KIN-CHUN MICHOUD CHRISTOPHE;

    申请日1999-12-17

  • 分类号A61K31/498;A61P29/00;C07D209/00;C07D241/00;C07D487/04;

  • 国家 CL

  • 入库时间 2022-08-22 00:45:55

相似文献

  • 专利
  • 外文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号