Use of a Pharmaceutical composition comprising N - 4 - (C 5hpirrol 2,1-a 1.4 benzodiazepines - (11h) - il - 10 - 3 chlorophenyl) carbonyl - 5 - fluoro - 2 - Methyl benzamide and one or more diuretics because it serves to increase urine flow with Minimal Loss of electrolytes or ionsPharmaceutical Composition and a kit comprising both components.

摘要

The Invention provides methods for Increasing the flow of urine in humans, while Minimizing the loss of electrolytes or ionsThese methods include the Administration even Human Needs, a combination of N - (4 - (5h pyrrolo (2,1) - C (1),4) 10 benzodiazepines - (11h) il 3 carbonyl - chlorophenyl) - 5-fluoro-2 - methylbenzamide (or a pharmaceutically acceptable Salt thereof), also known as vpa-985,And one or more agents, diuretics, and Pharmaceutical compositions and combinations of such equipment or Assemblies.