Pharmaceutical composition comprising N - 4 - (5H - 2.1 - pyrrole c 1,4 benzodiazepines - 10 - (11h) ilcarbonil 3-chlorophenyl - 5-fluoro-2 - methylbenzamide, a Surfactant, Polyethylene glycols,Sucrose Esters of fatty acid and / or polyvinylpyrrolidone, preparing procedure, useful as a diuretic.

摘要

The present Invention provides novel formulations of N - (4 - (5h pyrrolo (2.1) (1,4) - 10 benzodiazepines (11h) ilcarbonil) - (3-chlorophenyl) - 5-fluoro-2 - methylbenzamide,Or a pharmaceutically acceptable Salt thereof, and a process for their preparation, their formulations comprise from about 1% to about 20% of active ingredientsFrom about 1% to around 18% of a Surfactant Component, from about 50% to about 80% of a component of one or more Polietilen glycolsFrom about 1% to about 20% of a component made of one or more Fatty Acid Esters of sucrose and / or polyvinylpyrrolidone and optionally one or more preservatives and antioxidantIs pharmaceutically acceptable.