首页> 外国专利> Preparation containing An analog of Erythropoietin hiperglicosilada (NESP) preferably Chemically modified with polyethylene glycol (PEG), Pharmaceutical composition containing IT,Helpful for treating hematopoietic disorder.

Preparation containing An analog of Erythropoietin hiperglicosilada (NESP) preferably Chemically modified with polyethylene glycol (PEG), Pharmaceutical composition containing IT,Helpful for treating hematopoietic disorder.

机译:含有类似物,优选用聚乙二醇(PEG)化学修饰的促红细胞生成素hiperglicosilada(NESP)类似物的制剂,含有IT的药物组合物,对治疗造血系统疾病有帮助。

摘要

A substantially homogeneous preparation of Erythropoietin Stimulating Protein (NESP) Chemically modified oopcionalmente in a pharmaceutically acceptable diluent,Carrier or adjuvant. Pharmaceutical composition comprising: (a) a substantially homogeneous preparation of NESP Monkey.The NESP mono pegylated pegylated, consisting of a polyethylene glycol fragment attached to a fragment of NESP only in the n-terminal.(b) less than 5% of NESP non pegylated molecules; and (c) a Solvent, adjuvant or Carrier farmaceuiticamente acceptable.Use of such a preparation to treat hematopoietic disorder.
机译:在药学上可接受的稀释剂,载体或佐剂中的促红细胞生成素刺激蛋白(NESP)化学修饰的蛋白的基本均质的制剂。药物组合物,其包含:(a)NESP Monkey的基本上均质的制剂。NESP单聚乙二醇化的聚乙二醇化的,由仅在n-末端附接到NESP片段的聚乙二醇片段组成。(b)小于5%的NESP非聚乙二醇化分子(c)可接受的溶剂,佐剂或载体。该制剂用于治疗造血系统疾病的用途。

著录项

  • 公开/公告号CL2001000784A1

    专利类型

  • 公开/公告日2002-02-12

    原文格式PDF

  • 申请/专利权人 AMGEN INC.;

    申请/专利号CL2001000784

  • 申请日2001-04-05

  • 分类号A61K38/18;A61K47/48;A61P7/00;C07K14/475;

  • 国家 CL

  • 入库时间 2022-08-22 00:45:53

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