首页> 外国专利> Process for the preparation of a Pharmaceutical composition comprising the steps of (a) preparing a dispersion or solution of a homogeneous Fluid.Orlistat and excipients, and (b) subsequent expansion under conditions that do not Boil or dispersion solution; and the compositions obtained by this procedure.

Process for the preparation of a Pharmaceutical composition comprising the steps of (a) preparing a dispersion or solution of a homogeneous Fluid.Orlistat and excipients, and (b) subsequent expansion under conditions that do not Boil or dispersion solution; and the compositions obtained by this procedure.

机译:制备药物组合物的方法,该方法包括以下步骤:(a)制备均相的流体,奥利司他和赋形剂的分散液或溶液,以及(b)在不沸腾或分散液的条件下进行随后的膨胀;以及通过该程序获得的组合物。

摘要

The present Invention relates to a method for the preparation of compositions, Pharmaceutical compositions, preferably in the form of expanded Structures,Mechanically Stable, laminar, Porous, or in the form of Foam spongiform from Solutions and dispersions.This includes the steps of (a) preparation of a solution or a homogeneous dispersion of a liquid and a compound selected from the Group comprising one or more pharmaceutically Active compoundsYou, one or more pharmaceutically suitable excipients, and mixtures thereof, and (b) expansion of the solution or homogeneous dispersion without coming to the Boil.The Invention also relates to compositions, further processing and any corresponding dosage form obtainable by the method above.
机译:本发明涉及一种由溶液和分散体制备组合物,药物组合物的方法,所述组合物,药物组合物优选为膨胀结构,机械稳定,层状,多孔或泡沫海绵状的形式。这包括以下步骤: )制备液体和选自一种或多种药物活性化合物的化合物的溶液或均质分散液,一种或多种可药用赋形剂及其混合物,以及(b)溶液或均质分散液的扩展本发明还涉及通过上述方法可获得的组合物,进一步加工和任何相应的剂型。

著录项

  • 公开/公告号CL2001001480A1

    专利类型

  • 公开/公告日2002-07-03

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG.;

    申请/专利号CL2001001480

  • 发明设计人 SCHROEDER MARCO;BUSSON PATRICK;

    申请日2001-06-26

  • 分类号A61K9/20;

  • 国家 CL

  • 入库时间 2022-08-22 00:45:55

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