Compound Beta 3 adrenergic receptor agonists Compounds, Intermediates, Pharmaceutical composition containing them, useful for Treating Obesity and Type II diabetes.

摘要

The present Invention relates to a B3 adrenergic receptor agonist of formula I: or a Pharmaceutical Salt thereof, which is capable of increasing the liposis and expenditure of Energy in cellsAce, and is therefore useful for the treatment of Type II Diabetes and / or obesity.The compound can also be used to lower triglyceride levels and cholesterol levels or to raise high density lipoprotein levels or to reduce the mortalIntestinal activity. In addition, the compound can be used to reduce Neurogenic inflammation or as an antidepressant.Also described are compositions and procedures for the use of the compounds in the treatment of Diabetes and Obesity and to reduce triglyceride levels and levels dAnd raise the levels of cholesterol or High Density Lipoprotein or to reduce intestinal motility.