首页> 外国专利> Compounds derived from ondolil - 3 - 4 - phenyl - 1H pyrrole - 2.4 - dione, Process for preparing a Compound, Pharmaceutical composition,And its use for preparing Medicine useful in Alzheimer's disease, obesity, diabetes, ischemia, among others.

Compounds derived from ondolil - 3 - 4 - phenyl - 1H pyrrole - 2.4 - dione, Process for preparing a Compound, Pharmaceutical composition,And its use for preparing Medicine useful in Alzheimer's disease, obesity, diabetes, ischemia, among others.

机译:衍生自Ondolil-3-4-苯基-1H吡咯-2.4-二酮的化合物的制备方法,药物组合物及其在制备可用于阿尔茨海默氏病,肥胖症,糖尿病,局部缺血等疾病的药物中的用途。

摘要

The present Invention relates to Derivatives of 3 - indoli - 4 - phenyl - 2 - 1H pyrrole,5 - dione: formula (i) where R1 to R6 are the value given in the specification.The compounds are useful as inhibitors of glycogen synthase kinase 3B and, therefore, can be used for the treatment of diseases mediated by GSK - 3B.
机译:本发明涉及3-吲哚-4-苯基-2-1H吡咯,5-二酮的衍生物:式(i)其中R1至R6是说明书中给出的值。该化合物可用作糖原合酶激酶的抑制剂。 3B,因此可以用于治疗由GSK-3B介导的疾病。

著录项

  • 公开/公告号CL2001001772A1

    专利类型

  • 公开/公告日2002-05-24

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG.;

    申请/专利号CL2001001772

  • 发明设计人 GONGLEYI;ALLEN PELTZGARY.;GRUPEANDREW;

    申请日2001-07-26

  • 分类号A61K31/404;A61K31/5377;A61P11/06;A61P35/00;A61P37/08;C07D207/444;C07D209/28;C07D309/14;C07D317/22;C07D401/14;C07D403/14;C07D405/14;C07D413/14;

  • 国家 CL

  • 入库时间 2022-08-22 00:45:54

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