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Injectable naltrexone microsphere composition, form thereof suitable for injection administration, syringe containing the composition and use of the composition in reducing consumption of heroin and alcohol
Injectable naltrexone microsphere composition, form thereof suitable for injection administration, syringe containing the composition and use of the composition in reducing consumption of heroin and alcohol
An injectable slow-release naltrexone formulation is provided comprising naltrexone in a poly(D,L-lactide) matrix with a small amount of residual ethyl acetate. Upon intramuscular injection of the composition, naltrexone is released in a controlled manner over an extended period of time. The composition finds use in the treatment of heroin addicts and alcoholics to reduce consumption of the abused substances.
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