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INJECTABLE NALTREXONE MICROSPHERE COMPOSITIONS AND THEIR USE IN REDUCING CONSUMPTION OF HEROIN AND ALCOHOL
INJECTABLE NALTREXONE MICROSPHERE COMPOSITIONS AND THEIR USE IN REDUCING CONSUMPTION OF HEROIN AND ALCOHOL
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机译:注射用纳曲酮微球组合物及其在减少海洛因和酒精消费中的用途
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摘要
An injectable slow-release naltrexone formulation is provided comprising naltrexone in a poly(D,L-lactide) matrix with a small amount of residual ethyl acetate. Upon intramuscular injection of the composition, naltrexone is released in a controlled manner over an extended period of time. The composition finds use in the treatment of heroin addicts and alcoholics to reduce consumption of the abused substances.
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