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Novel cephalosporins containing, at the 7-position, a substituted benzyloxyimino group, methods and intermediates, and their use as drugs
Novel cephalosporins containing, at the 7-position, a substituted benzyloxyimino group, methods and intermediates, and their use as drugs
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机译:在7位上含有取代的苄氧基亚氨基的新型头孢菌素,方法和中间体及其作为药物的用途
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摘要
Syn isomer of cpds. of formula (I), and their salts, are new. In (I), R1-R3, R5 = H, halo, OH, 1-4C alkyl (opt. substd. by halo, 1-4C alkyloxy, SH etc.); R4 = OH or 1-8C acyloxy; R7 = H or (1-3C alkyloxy)carbonyl; A = e.g. H, an equivalent of alkali(ne earth) metal, Mg, ammonium or aminated organic base etc.; or CO2A = CO2-; wavy line shows that CH2R6 can be in E- or Z-position; R6 = e.g. quat. ammonium or gp. of formula (i); X = CH2, NH, O or S; and Y, T, U, V, W and Z = CH or N; with the provisos.
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