Combination of an opioid antagonist and a selective serotonin reuptake inhibitor to treat alcoholism and alcohol dependence

摘要

The invention relates to a method of treating alcoholism and alcohol dependence in a mammal comprising administering to the mammal a therapeutically effective amount of a synergistic combination of: (i) at least one opioid antagonist, and (ii) at least one selective serotonin reuptake inhibitor. The invention also relates to compositions and kits containing the same.