PHARMACEUTICAL COMPOSITION CONTAINING (R)-3-N,N-DICYKLOBUTYLAMINO-8-FLUORO-3,4-DIHYDRO-2H-1-BENZOPYRAN-5-CARBOXAMIDE HIDROGEN-(2R,3R)TARTARATE MONOHYDRATE AND PAROXETIN AND PROCESS FOR ITS PREPARATION

摘要

The present invention relates to (R) -3- (N, N-dicyclobutylamino) -8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen (2R) as the first component (a). 3R) -tartrate monohydrate and the second component (b) is paroxetine in the form of the free base or a pharmaceutically acceptable salt and / or solvate thereof. The invention further relates to the manufacture of a composition, pharmaceutical compositions containing the composition and their use in the treatment of irritable disorders such as mood disorders and anxiety disorders, and a kit comprising the composition. SHE