PHARMACEUTICAL COMPOSITION CONTAINING (R)-3-N,N-DICYKLOBUTYLAMINO-8-FLUORO-3,4-DIHYDRO-2H-1-BENZOPYRAN-5-CARBOXAMIDE HIDROGEN-(2R,3R)TARTARATE MONOHYDRATE AND PAROXETIN AND PROCESS FOR ITS PREPARATION

摘要

The invention relates to a composition comprising a first component (a) which is (R)-3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen (2R,3R)-tartrate monohydrate and a second component (b) which is paroxetine in the form of its free base, or a pharmaceutically acceptable salt and/or solvate thereof, the preparation thereof, pharmaceutical formulations containing said composition, use of and a method of treatment of affective disorders such as mood disorders and anxiety disorders with said composition as well as a kit containing said composition.