首页> 外国专利> 12H-DIBENZO d,g 1,3 DIOXOCINE SUBSTITUTED N-HETEROCYCLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

12H-DIBENZO d,g 1,3 DIOXOCINE SUBSTITUTED N-HETEROCYCLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

机译:12H-二苯并[d,g] [1,3]二恶英取代的N杂环衍生物,其制备和组成它们的药物成分

摘要

The present invention relates to novel N-substituted amino alcohols, amino acids and acid derivatives thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
机译:本发明涉及新颖的N-取代的氨基醇,氨基酸及其酸衍生物,其中取代的烷基链构成N-取代基的一部分或其盐,其制备方法,含有它们的组合物及其用途用于临床治疗疼痛,痛觉过敏和/或炎性疾病,其中C纤维通过引起神经源性疼痛或炎症而发挥病理生理作用。

著录项

  • 公开/公告号IL123424A

    专利类型

  • 公开/公告日2002-02-10

    原文格式PDF

  • 申请/专利权人 NOVO NORDISK A/S;

    申请/专利号IL19960123424

  • 发明设计人

    申请日1996-09-12

  • 分类号C07D273/06;C07D321/06;C07D405/06;C07D413/06;A61K31/357;A61K31/395;A61P5/48;

  • 国家 IL

  • 入库时间 2022-08-22 00:45:01

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