首页>
外国专利>
ISOLATED AMPHIPHILIC PEPTIDES DERIVED FROM THE CYTOPLASMIC TAIL OF VIRAL ENVELOPE PROTEINS
ISOLATED AMPHIPHILIC PEPTIDES DERIVED FROM THE CYTOPLASMIC TAIL OF VIRAL ENVELOPE PROTEINS
展开▼
机译:病毒包膜蛋白的胞浆尾分离的两亲性肽
展开▼
页面导航
摘要
著录项
相似文献
摘要
An isolated peptide comprising an amino acid sequence derived from a viral envelope protein, wherein at least a portion of the amino acid sequence is located within the cytoplasmic tail or membrane-spanning region of a viral envelope protein. Such peptides are amphiphilic in nature, provide for the destabilization of membranes, and facilitate the entry of viral particles into cells and the efficient formation of viral particles. The peptides may, in another embodiment, be attached to the viral membrane, along with a targeting polypeptide, as part of an artificial viral envelope protein.
展开▼