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COMBINATION OF A 5-HT ABSORPTION INHIBITOR WITH A SELECTIVE 5-HT1A ANTAGONIST
COMBINATION OF A 5-HT ABSORPTION INHIBITOR WITH A SELECTIVE 5-HT1A ANTAGONIST
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机译:5-HT吸收抑制剂与选择性5-HT1A拮抗剂的组合
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摘要
The invention relates to a composition comprising a first component (a) which is (R)-3N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen (2R,3R)-tartrate monohydrate and a second component (b) which is 1-[3-(dimethylamino)propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile, as the racemate or an enantiomer thereof, in the form of the free base, or a pharmaceutically acceptable salt and/or solvate thereof The invention further concerns the preparation of the composition, pharmaceutical formulations containing said composition, and a method of treatment of affective disorders such as mood disorders and anxiety disorders with said composition, as well as a kit containing said composition.
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