A COMBINATION OF A 5-HT UPTAKE INHIBITOR WITH A SELECTIVE 5-HT1A ANTAGONIST

摘要

The combination of the first 5-HT reuptake inhibitor component and the second 5-HT1A selective antibody of formula (I) wherein R 1 is n-propyl or cyclobutyl, R 2 is isopropyl, tertiary butyl, cyclobutyl, cyclopentyl or cyclohexyl, R 3 is hydrogen, R 4 is hydrogen or methyl, such as the (R) -enantiomer in free base form or pharmaceutically acceptable salts thereof, a process for its preparation, a pharmaceutical formulation comprising said combination, its use for improving the treatment of emotional disorders and a content kit of said combination