COMBINATION OF A PROGESTATIONAL AGENT AND A NITRIC OXIDE SYNTHASE SUBSTRATE AND/OR DONOR FOR THE TREATMENT OF PREECLAMPSIA AND PRETERM LABOR

摘要

A progestational agent in combination with a nitric oxide synthase substrate, a nitric oxide donor, or both, optionally in combination with one or more cyclooxygenase inhibitors, PGI2-mimetics, thromboxane inhibitor (TXA2), a compound having TXA2-agonist and TXA2-inhibiting properties, a compound having TXA2-antagonist and PGI2-mimetic activities, and TXA2 agonists, are used for the preparation of a medicament for the treatment of pre-eclampsia and premature labor in a pregnant female mammal.