the gene of streptomyces avermitilis commander of avermectin b2: b1 and a new process for production of avermectins.

摘要

the invention relates to molecules containing sequences encoding a polynucleotidiques gene product, change the ratio of 2: 1 of avermectins in the cultures of s.avermitilis by fermentation. it is also the host cells and vectors, mutant strains in which the gene with s.avermitilis was inactive or mute.application: use of the avermectin compounds and compositions as parasiticides.