VERF YEARS FOR THE DETECTION AND EVALUATION OF A POTENTIALLY aberrantly methylated DNA-REGION AT X-CHROMOSOME OR clonality

摘要

The invention relates to a method for detecting and evaluating a potentially aberrantly methylated DNS region on the X chromosome or the clonality. The extend of the methylation of the potentially aberrantly methylated DNS region and optionally the extend of the methylation in a securely physiologically methylated DNS area of the X chromosome and/or the extend of the methylation as well as optionally the sequence variant of a polymorphous DNS region of the X-chromosome is/are determined in a sample, whereby said variant can be methylated physiologically or aberrantly. The presence and optionally the variant and the extend of the potential aberration or the clonality is/are subsequently diagnosed by comparing the determined methylations and optionally the sequence variant.