ANTI-ENDOGLINE MONOCLONAL ANTIBODIES AND ITS USE IN ANTI-ANGIOGENESIS THERAPY.

摘要

THE PRESENT INVENTION REFERS TO A MONOCLONAL ANTIBODY, OR FRAGMENTS OF THE SAME, THAT HAS SPECIFICITY OF BOTH UNION FOR ENDOGLINE EXPRESSED IN PROLIFERATIVE HUMAN VASCULAR ENDOTELIAL CELLS AND FOR ENDOGLINE EXPRESSED IN PROHLIMERATIVE CELLS. THE ANTIANGIOGENIC THERAPY IN MAMIFEROS CAN BE CARRIED OUT BY ADMINISTRATION TO A MAMMAL GUEST OF A THERAPEUTICALLY EFFECTIVE AMOUNT OF SUCH ANTIENDOGLINE MONOCLONAL ANTIBODY OR FRAGMENTS OF THE SAME UNIVERSAL AGE AT THE same time. THE COMPOSITION IS USEFUL TO TREAT DISEASES ASSOCIATED WITH ANGIOGENESIS AND TUMORS.