首页> 外国专利> FUSED GENES AND THEIR USE FOR DETERMINING THE PRESENCE OF METALS OR OF XENOBIOTIC COMPOUNDS

FUSED GENES AND THEIR USE FOR DETERMINING THE PRESENCE OF METALS OR OF XENOBIOTIC COMPOUNDS

机译:融合基因及其在确定金属或异种化合物存在中的用途

摘要

The invention relates to a fused gene containing: the promoter sequence of (a)gene(s) encoding the resistance to one orseveral metal(s) or encoding the catabolism of one or several xenobioticcompound(s), said promoter being inducible in the pres-ence of said metal(s) or xenobiotic compound(s), or both, and downstream thepromoter, a gene producing a detectable signalsuch as light emitting gene, said gene being under the control of saidpromoter, said gene producing a detectable signal being lo-cated at a position such that the induction of the promoter causes thetranscription of the gene producing a detectable signal andsuch that there is no terminator between the promoter and the gene producing adetectable signal.
机译:本发明涉及一种融合基因,其包含:(a)的启动子序列编码对一种或多种抗药性的基因几种金属或编码一种或几种异生物的分解代谢化合物,所述启动子可在pres-中诱导所述金属或异种生物化合物或两者的结合以及下游的启动子,产生可检测信号的基因例如发光基因,所述基因处于所述基因的控制之下。启动子,所述产生可检测信号的基因是lo-放置在这样的位置,使得启动子的诱导导致产生可检测信号的基因的转录和这样在启动子和产生a的基因之间没有终止子可检测的信号。

著录项

  • 公开/公告号CA2105172C

    专利类型

  • 公开/公告日2002-10-15

    原文格式PDF

  • 申请/专利权人 VITO;

    申请/专利号CA19922105172

  • 申请日1992-02-28

  • 分类号C12N15/62;C12N1/20;C12N15/31;C12N15/53;C12Q1/66;C12Q1/68;

  • 国家 CA

  • 入库时间 2022-08-22 00:41:19

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