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P43 anti-tumor therapeutic agent and three dimensional structure of its cytokinedomain
P43 anti-tumor therapeutic agent and three dimensional structure of its cytokinedomain
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机译:P43抗肿瘤治疗剂及其细胞因子结构域的三维结构
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摘要
The object of the present invention is to provide an anti-tumor and anti-angiogenic agent of p43 (SEQ ID NO : 2) consisting of two domains, N-terminal domain (146 amino acids) and C-terminal domain (166 amino acids), wherein C-terminal domain consists of 11 beta -strands forming a structural core and 3 flanking alpha -helices.
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机译:本发明的目的是提供一种p43(SEQ ID NO:2)的抗肿瘤和抗血管生成剂,其由两个结构域组成,即N端结构域(146个氨基酸)和C端结构域(166个氨基酸)。 ),其中C端结构域由11个形成结构核心的β-链和3个侧翼的α-螺旋组成。
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