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System and method for heating the prostate gland to treat and prevent the growthand spread of prostate tumors

机译:用于加热前列腺以治疗和预防前列腺肿瘤的生长和扩散的系统和方法

摘要

A system and method for safely heating cancerous and pre-cancerous conditions of the prostate, as well as benign and pre-benign lesions (any localized pathological change in the prostate tissue) by irradiation of the prostate tissue with coherent phased array or non-coherent energy is introduced. Microwave energy and prostate compression provide preferential heating of high-water content prostate carcinoma and benign cells in the prostate compared to the surrounding lower-water content normal prostate tissues and tissue surrounding the prostate. To coherently focus the energy, such as microwave energy, in the prostate, the patient's prostate can be compressed via a urethral and rectal balloon and either a single electric-field probe, inserted in the central portion of the prostate, or two noninvasive electric-field sensors on the urethral and rectal walls, can be used to measure a feedback signal to adjust the energy phase delivered to the applicators located in the urethra and in the rectum. The initial energy power delivered to the energy applicators is set to a desired value that is known to produce a desired increase in temperature in the prostate. Temperature feedback sensors are used to measure urethral and rectal wall temperatures during treatment to adjust the energy power delivered to the applicators to avoid overheating the urethral and rectal walls. The energy delivered to the applicators is monitored in real time during treatment, and the treatment is completed when a desired total energy dose has been administered.
机译:一种通过相干相控阵或非相干相干照射前列腺组织来安全地加热前列腺癌和癌前病变以及良性和良性病变(前列腺组织中任何局部病理变化)的系统和方法引入能量。与周围较低水分含量的正常前列腺组织和周围前列腺组织相比,微波能量和前列腺压缩可优先加热高水分含量的前列腺癌和前列腺中的良性细胞。为了将能量(例如微波能量)集中地集中在前列腺中,可以通过尿道和直肠球囊以及插入前列腺中心部分的单个电场探头或两个非侵入性电探针来压缩患者的前列腺。尿道和直肠壁上的现场传感器可用于测量反馈信号,以调节传递至位于尿道和直肠中的涂抹器的能量相位。传递至能量施加器的初始能量功率被设置为期望值,该期望值已知会在前列腺中产生期望的温度升高。温度反馈传感器用于在治疗过程中测量尿道和直肠壁的温度,以调节输送至涂抹器的能量,从而避免尿道和直肠壁过热。在治疗过程中实时监控输送到施药器的能量,并在完成所需的总能量剂量后完成治疗。

著录项

  • 公开/公告号AU6995001A

    专利类型

  • 公开/公告日2002-01-02

    原文格式PDF

  • 申请/专利权人 CELSION CORPORATION;

    申请/专利号AU20010069950

  • 发明设计人 ALAN J. FENN;JOHN MON;

    申请日2001-06-20

  • 分类号G01N25/16;

  • 国家 AU

  • 入库时间 2022-08-22 00:39:30

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