(2-azabicyclo(2.2.1)hept-7-yl)methanol derivatives as nicotinic acetylcholine receptor agonists

摘要

The present invention relates to substances of the general formula (I) in which X is selected from the group consisting of NH, NRSUP4/SUP, O and S, RSUP1 /SUPis selected from the group consisting of hydrogen, linear and branched, substituted and unsubstituted CSUB1/SUB-CSUB10/SUB-alkyl groups, substituted and unsubstituted CSUB5/SUB-CSUB10/SUB-aryl groups, substituted and unsubstituted CSUB4/SUB-CSUB10/SUB-heteroaryl groups, acyl groups, thioacyl groups, carbonylcarboxy groups, N-organyl-substituted carbamoyl groups and organosulfonyl groups, RSUP2/SUP, RSUP3 /SUPare selected, independently of one another, from the group consisting of CSUB1/SUB-CSUB10/SUB-alkyl groups, CSUB5/SUB-CSUB12/SUB-aryl groups and CSUB4/SUB-CSUB12/SUB-heteroaryl groups, these groups being unsubstituted or having one or more substituents which are selected, independently of one another, from the group consisting of halogens, alkoxy groups, aryloxy groups, nitro groups, CSUB1/SUB-CSUB5/SUB-alkoxycarbonyl groups, optionally fluorine-substituted alkyl or acyl groups and cyano groups, RSUP4 /SUPis selected from the group consisting of hydrogen, linear and branched, substituted and unsubstituted CSUB1/SUB-CSUB10/SUB-alkyl groups, substituted and unsubstituted CSUB5/SUB-CSUB10/SUB-aryl groups, substituted and unsubstituted CSUB4/SUB-CSUB10/SUB-heteroaryl groups, aryl groups, thioacryl group, carbonylcarboxy groups, N-organyl-substituted carbamoyl groups and organosulfonyl groups, or a physiologically acceptable salt thereof.