5-hydroxytryptamine receptor gene polymorphisms and response to treatment

摘要

Correlations between polymorphisms in the 5-hydroxytryptamine 3 receptor gene, and/or polymorphisms in the UGT1A4 gene, and a subject's phenotypic response to treatment with 5-hydroxytryptamine ligands are described. Methods of screening subjects to aid in treatment, methods of screening 5HT ligands, and methods of treatment are presented.