METHOD FOR RECELLULARIZATION OF A DECELLULARIZED HEART VALVE AND HEART VALVE PRODUCED THEREBY

摘要

A method for producing a non-immunogenic and durable living graft involves the recellularization of a decellularized heart valve allograft or xenograft by recipient cells after implantation of such graft into a living patient. Decellularized allograft or xenograft grafts which have not been exposed to a cytotoxic environment are treated with either chemotactic factors or cell adhesion factors, or both, to retain desirable recipent cells into the tissue graft after implantation.