A NEW POLYPEPTIDE-HUMAN FK506 BINDING PROTEIN 12.32 AND THE POLYNUCLEOTIDE ENCODING IT

摘要

The present invention disclose a new polypeptide-human FK506 binding protein 12.32, the polynucleotide encoding it and a method producing the polypeptide by DNA recombinant technology. The present invention further disclose a method using the peptide for treating various disorders, e.g., immunological disturbance, congenital cardiovascular abnormality, cardiac muscle contraction disturbance disorder, skeletal muscle contraction disturbance disorder etc. The present invention also disclose an antagonist of the polypeptide and its therapeutic action. The present invention further disclose the use of the polynucleotide encoding the new human FK506 binding protein 12.32.