DESIGN AND PRODUCTION OF MUTANT 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE ENZYMES WITH ALTERED COFACTOR DEPENDENCY

摘要

Methods for producing mutant 2,5-diketo-D-gluconic acid reductase enzymes with altered cofactor dependency are provided. Also provided are mutant 2,5-diketo-D-gluconic acid reductase enzymes with altered cofactor dependency, DNA encoding these mutant enzymes, and vectors and host cells expressing these mutant enzymes.