GENETIC FACTORS AFFECTING THE OUTCOME OF VIRAL INFECTIONS

摘要

There is disclosed a method of predicting the outcome of a viral infection in a human subject, the method comprising screening for the presence or absence in the genome of said subject of one or more polymorphic variants of the IL10RB gene or of one or more polymorphic variants in linkage disequilibrium with or in close physical proximity to a polymorphic locus in the IL10RB gene. The method is particularly useful as a genetic screen to predict the outcome of diseases caused by hepatitis B virus, hepatitis C virus and HIV.