首页>
外国专利>
INHIBITION OF ARTERIAL SMOOTH MUSCLE CELL PROLIFERATION
INHIBITION OF ARTERIAL SMOOTH MUSCLE CELL PROLIFERATION
展开▼
机译:抑制动脉平滑肌细胞增殖
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method for inhibiting restenosis associated with mechanical injury of a blood vessel. An adenoviral vector encoding a suicide gene such as thymidine kinase is directly administered to the injured vessel followed by treatment with a nucleotide analog. The analog is phosphorylated and converted to a cytotoxin by the suicide gene product, resulting in destruction of the rapidly dividing neointimal cells.
展开▼