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INHIBITORS OF HUMAN RHINOVIRUS 2A CYSTEINE PROTEASE
INHIBITORS OF HUMAN RHINOVIRUS 2A CYSTEINE PROTEASE
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机译:人类鼻病毒2A半胱氨酸蛋白酶的抑制剂
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摘要
Compounds of formula I are effective inhibitors of human rhinovirus 2A protease: (I) where R1 is H, lower alkyl, lower alkenyl, lower alkynyl, lower acyl, or lower acyloxy, substituted with 0-3 substituents selected from the group consisting of OH, halo, amino, nitro; R2 is H, lower alkyl, OH, halo, or amino; R3, R4, R5, R6, and R7 are each independently H, halo, OH, amino, nitro, lower alkyl, aryl, aralkyl, lower alkoxy, or lower alkylamino; or a pharmaceutically acceptable salt thereof.
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机译:式I化合物是人鼻病毒2A蛋白酶的有效抑制剂:(I)其中R1为H,被0-3个选自OH的取代基取代的H,低级烷基,低级烯基,低级炔基,低级酰基或低级酰氧基。 ,卤素,氨基,硝基; R 2是H,低级烷基,OH,卤素或氨基; R3,R4,R5,R6和R7分别独立地为H,卤素,OH,氨基,硝基,低级烷基,芳基,芳烷基,低级烷氧基或低级烷基氨基;或其药学上可接受的盐。
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