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TRANSGENIC MOUSE HAVING A LacZ REPORTER GENE UNDER THE CONTROL OF THE N-CAM PROMOTER
TRANSGENIC MOUSE HAVING A LacZ REPORTER GENE UNDER THE CONTROL OF THE N-CAM PROMOTER
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机译:在N-CAM启动子的控制下具有LacZ报告基因的转基因小鼠
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摘要
The invention describes a transgenic mouse having a knockout N-CAM allele with an insertion of a reporter gene under the control of the N-CAM promoter. In preferred embodiments, the reporter gene encodes beta-galactosidase. The invention also describes methods for detecting modulators of the N-CAM gene using the transgenic mouse, or cultured cells obtained from the mouse.
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