首页>
外国专利>
METHOD OF AFFECTING CHOLESTEROL CATABOLISM USING NUCEAR BILE ACID RECEPTOR
METHOD OF AFFECTING CHOLESTEROL CATABOLISM USING NUCEAR BILE ACID RECEPTOR
展开▼
机译:利用核胆汁酸受体影响胆固醇代谢的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to methods and compositions for modulating genes which are controlled by the FXR orphan nuclear hormone receptor. In a preferred embodiment, the method involves modulation of the gene encoding Cyp7a, the enzyme responsible for a major pathway in the elimination of cholesterol. The invention also relates to methods for screening compounds which bind to and activate or inhibit the FXR nuclear hormone receptor.
展开▼