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USE OF FUCOSYLATED SIALYLATED N-ACETYL LACTOSAMINE CARBOHYDRATE STRUCTURES FOR INHIBITION OF BACTERIAL ADHERENCE
USE OF FUCOSYLATED SIALYLATED N-ACETYL LACTOSAMINE CARBOHYDRATE STRUCTURES FOR INHIBITION OF BACTERIAL ADHERENCE
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机译:使用岩藻糖基化的N-乙酰乳酸氨水合氨基甲酸酯结构抑制细菌粘附
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摘要
A fucosylated sialylated N-acetyl lactosamine structure such as a sialyl-Lewis antigen carbohydrate structure, for example sialyl-Lewis x and in particular dimeric or repetitive sialyl-Lewis x can be used for the preparation of a pharmaceutical composition for the treatment or prophylaxis in humans of conditions involving infection by Helicobacter pylori and related pathogens of the human gastrointestinal mucosa. Further, said conditions can be treated through the administration of a fucosylated sialylated lactosamine structure, such as a sialyl-Lewis antigen carbohydrate structure or corresponding antibodies to patients in need thereof.
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