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INDUCIBLE PACKAGING CELL LINES FOR LENTIVIRUS VECTORS
INDUCIBLE PACKAGING CELL LINES FOR LENTIVIRUS VECTORS
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机译:慢病毒载体的可包装包装细胞系
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摘要
Novel packaging cell lines for production of lentiviral vectors are disclosed. The cell lines utilize an ecdysone-inducible system for virus production, thereby avoiding the cytotoxic effect of unregulated expression of certain envelope proteins and lentiviral proteins. Various embodiments of the cell lines are disclosed, which are suitable for different purposes that range from in vitro screening assays to gene therapy in vivo.
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