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FIBROSIS INHIBITORS CONTAINING AS THE ACTIVE INGREDIENT SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST OR SPHINGOSINE-1-PHOSPHATE

机译：活性成分为新蛋白-1-磷酸受体激动剂或新蛋白-1-磷酸的成纤维抑制剂

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摘要

An anti fibrotic agent, comprising a sphingosine 1-phosphate (S1P) receptor agonist or sphingosine 1-phosphate (S1P) as an active ingredient. Since an S1P receptor agonist, particularly S1P, has activity of inhibiting fibrosis in various organs, it is useful in preventing and/or treating diseases caused by fibrosis in organs, such as pulmonary fibrosis, interstitial pneumonia, chronic hepatitis, hepatic cirrhosis, chronic renal failure, renal glomerulosclerosis, etc.

机译：一种抗纤维化剂，其包含1-磷酸鞘氨醇（S1P）受体激动剂或1-磷酸鞘氨醇（S1P）作为有效成分。由于S1P受体激动剂，特别是S1P，具有抑制各种器官纤维化的活性，因此可用于预防和/或治疗由器官的纤维化引起的疾病，例如肺纤维化，间质性肺炎，慢性肝炎，肝硬化，慢性肾脏病衰竭，肾小球硬化，等 展开▼

著录项

公开/公告号EP1195165A1

专利类型

公开/公告日2002-04-10

原文格式PDF

申请/专利权人 ONO PHARMACEUTICAL CO. LTD.;
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申请/专利号EP20000944365

发明设计人 KISHIKAWA KATSUYAONO PHARMACEUTICAL CO. LTD.;MATSUMOTO SHIGERUONO PHARMACEUTICAL CO. LTD.;
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申请日2000-07-10

分类号A61K45/00;A61K31/661;

国家 EP

入库时间 2022-08-22 00:33:37

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