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QUANTITATIVE ANALYSIS AND TYPIFICATION OF SUBCELLULAR PARTICLES

机译:亚细胞颗粒的定量分析和分型

摘要

The invention relates to a method for determining and individually characterizing particles by means of at least two different detectable probes in a sample. According to said method, the particles, especially molecules or molecule aggregates, have at least one binding site, preferably a number of binding sites for at least one of the at least two different detectable probes. The at least two different detectable probes are present in the sample. A measure for the number of bound probes and the relationship between the bound probes are established by determining particles, this determination taking place on the basis of individual particles.
机译:本发明涉及用于通过样品中的至少两种不同的可检测探针确定和单独表征颗粒的方法。根据所述方法,颗粒,尤其是分子或分子聚集体,具有至少一个结合位点,优选地,至少两个不同的可检测探针中的至少一个具有多个结合位点。样品中存在至少两种不同的可检测探针。通过确定颗粒来确定结合探针的数量和结合探针之间的关系的量度,该确定基于单个颗粒进行。

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