首页>
外国专利>
Peroxisome proliferator-activated receptor gamma ligand eluting medical device
Peroxisome proliferator-activated receptor gamma ligand eluting medical device
展开▼
机译:过氧化物酶体增殖物激活受体γ配体洗脱医疗设备
展开▼
页面导航
摘要
著录项
相似文献
摘要
Implantable medical devices having an anti-restenotic coatings are disclosed. Specifically, implantable medical devices having coatings of peroxisome proliferator-activated receptor gamma (PPARy) agonists are disclosed. The anti-restenotic PPARy ligands include thiazolidinedione compounds including ciglitazone. The anti-restenotic medial devices include stents, catheters, micro-particles, probes and vascular grafts. The medical devices can be coated using any method known in the art including compounding the thiazolidinedione with a biocompatible polymer prior to applying the coating. Moreover, medical devices composed entirely of biocompatible polymer-thiazolidinedione blends are disclosed. Additionally, medical devices having a coating comprising at least one thiazolidinedione in combination with at least one additional therapeutic agent are also disclosed. Furthermore, related methods of using and making the anti-restenotic implantable devices are also disclosed.
展开▼