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SOLID LIPID NANOPARTICLE AS A GENE OR DRUG CARRIER FORMULATION AND METHOD FOR PREPARATING THEREOF

机译:作为基因或药物载体的固体脂质纳米颗粒及其制备方法

摘要

PURPOSE: Provided are a solid lipid nanoparticle as a gene or drug carrier, a formulation, and a method for preparing the same, thereby effectively transferring DNAs, bioprobes and drugs to the target cells. CONSTITUTION: The solid lipid nanoparticle comprises: a) at least one solid lipid nanoparticle material selected from C12-18 triglyceride or ethyl stearate, 2-30%; b) at least one kind of emulsifier including cationic surfactants, 0.01-20%; and c) the balance of water.
机译:目的:提供作为基因或药物载体的固体脂质纳米颗粒,制剂及其制备方法,从而有效地将DNA,生物探针和药物转移至靶细胞。组成:固体脂质纳米颗粒包括:a)至少一种选自C12-18甘油三酸酯或硬脂酸乙酯的固体脂质纳米颗粒材料,占2-30%; b)至少一种乳化剂,包括0.01-20%的阳离子表面活性剂; c)水的平衡。

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