首页> 外国专利> Identification of Candida Albicans Essential Fungal Specific Genes and Use Thereof in Antifungal Drug Discovery

Identification of Candida Albicans Essential Fungal Specific Genes and Use Thereof in Antifungal Drug Discovery

机译：白色念珠菌必需真菌特异性基因的鉴定及其在抗真菌药物发现中的应用

页面导航

摘要
著录项
相似文献

摘要

The invention of the yeast pathogen Candida albicans (Candidaalbicans, C.albicans), the fungal specific essential gene, i.e. CaKRE 5, CaALRCaCDC 1 and relates to the verification and destruction of the 24 fungal diagnostics and anti-fungal drug is isolated from for development it relates to the essential antifungal targets as their use in fungal species. More particularly, the present invention relates to CaKRE 5, CaALR 1 and CaCDC 24 gene, and the use thereof, and thus the identified drug in the screening for the anti-fungal compound.

机译：酵母病原体白色念珠菌（Candida albicans，C。 albicans）的发明是真菌特异性必需基因，即 CaKRE < / I> 5， CaALR CaCDC 1，涉及24种真菌诊断剂的验证和破坏，并且从开发中分离出抗真菌药物，它与必需的抗真菌药物有关目标是它们在真菌物种中的用途。更具体地，本发明涉及 CaKRE 5， CaALR 1和 CaCDC 24基因，及其用途，因此涉及鉴定的药物。筛选抗真菌化合物。 展开▼

著录项

公开/公告号KR20020047034A

专利类型

公开/公告日2002-06-21

原文格式PDF

申请/专利权人 제임스 이 알브라이트;
展开▼

申请/专利号KR20017014107

发明设计人 로에머테리;부시하워드;데이비슨존;
展开▼

申请日2001-11-05

分类号C12Q1/68;

国家 KR

入库时间 2022-08-22 00:30:52

相似文献

专利

外文文献

中文文献

1. 白色念珠菌(C.Albicans)中的必需基因及用该基因筛选抗真菌物质的方法 [P] . 中国专利： CN1331753A . 2002-01-16

2. 毛果杨HDA909基因在提高植物抗真菌能力中的应用 [P] . 中国专利： CN112430602A . 2021-03-02

3. Identification of Candida albicans essential fungal specific genes and use thereof in antifungal drug discovery [P] . 美国专利： US7129341B1 . 2006-10-31

机译：白化念珠菌必需真菌特异性基因的鉴定及其在抗真菌药物发现中的应用

4. Identification of candida albicans essential fungal specific genes and use thereof in antifungal drug discovery [P] . NZ515253A . 2004-10-29

机译：白色念珠菌必需真菌特异性基因的鉴定及其在抗真菌药物发现中的应用

5. IDENTIFICATION OF CANDIDA ALBICANS ESSENTIAL FUNGAL SPECIFIC GENES AND USE THEREOF IN ANTIFUNGAL DRUG DISCOVERY [P] . 欧洲知识产权局专利： EP1173619A2 . 2002-01-23

机译：白化念珠菌必需真菌特异性基因的鉴定及其在抗真菌药物发现中的应用

1. Candida albicans isolated from urine: Phenotypic and molecular identification, virulence factors and antifungal susceptibility [J] . Laura Wiebusch, Bruna de Paula Bicudo, Danielle Ferreira Lonchiati, 亚太热带生物医学杂志（英文版） . 2017,第007期

2. Candida albicans isolated from urine: Phenotypic and molecular identification, virulence factors and antifungal susceptibility [J] . Laura Wiebusch, Adriana Araújo de Almeida-Apolonio, Luana Mireli Carbonera Rodrigues, 亚太热带生物医学杂志：英文版 . 2017,第007期

3. Genotyping and Antifungal Susceptibility Profile of Sequential Candida albicans Isolated from the Oral Cavity of HIV-Infected Individuals [J] . Daniela Vanessa Moris, Joyce Marinho de Souza, Marcia Souza Carvalho Melhem, 药剂与药理学：英文版 . 2018,第004期

4. Effect of antifungal agents on non-Candida albicans Candida species enzymatic activity [C] . M. Negri, T. Loren?o, S. Silva, International Conference on Antimicrobial Research . 2011

5. Stress Response Pathways Regulate Drug Resistance and Morphogenesis in the Human Fungal Pathogen Candida albicans [D] . Xie, Jing Lin 2017

6. Effects of Depleting the Essential Central Metabolic Enzyme Fructose-16-Bisphosphate Aldolase on the Growth and Viability of Candida albicans: Implications for Antifungal Drug Target Discovery [O] . Alexandra Rodaki, Tim Young, Alistair J. P. Brown 2006

7. Effects of Depleting the Essential Central Metabolic Enzyme Fructose-1,6-Bisphosphate Aldolase on the Growth and Viability of Candida albicans: Implications for Antifungal Drug Target Discovery [O] . Rodaki, Alexandra, Young, Tim, Brown, Alistair J. P. 2006

1. Antifungal activity of chemotype essential oils from rosemary against iCandida albicans/i [J] . Yusuke Matsuzaki ,Toshiyuki Tsujisawa ,Tatsuji Nishihara . 口腔学期刊（英文） . 2013,第2期

2. Antifungal Activity of Schinifoline Against Candida Albicans in Caenorhabditis Elegans [J] . Chengjie Shu ,Mengli Zhang ,Weiming Zhang . 国际实验植物学杂志(英文) . 2019,第3期

3. ITS基因序列分析在鉴定暗色真菌中的应用 [C] . ZHANG Wei-zheng ,张伟铮 ,XIAO Qian . 第一次全国中西医结合检验医学学术会议 . 2014

4. 抗真菌乳酸菌的抗菌成分分离鉴定及在奶酪保鲜中的应用 [A] . 萨仁 . 2021