Substituted arylalkynyl- and heteroarylalkynyl-N-hydroxyureas as leukotriene biosynthesis inhibitors

摘要

The present invention relates to compounds having the ability to inhibit lipoxygenase enzyme activity, pharmaceutical compositions containing them and methods of medical treatment thereof. More particularly, the present invention relates to certain substituted arylalkynyl- and ((heteroaryl) alkynyl) -N-hydroxy-ureas, which inhibit leukotriene biosynthesis, pharmaceutical compositions containing them and methods of inhibiting leukotriene biosynthesis It is about.