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METHOD FOR DETERMINING PREDISPOSITION TO OPIATE ADDICTION

机译:确定阿片成瘾倾向的方法

摘要

FIELD: medicine. SUBSTANCE: method involves in vitro determining cyclic adenosine monophosphate concentration under test loading with morphine in combination with noloxon in native cells and native morphinized mononuclear cells of peripheral blood. Predisposition index is calculated by dividing cyclic adenosine monophosphate concentration in native premorphinized cells by the value in mononuclear cells. The value being greater than 1.3, high level of predisposition to opiate addiction. EFFECT: enhanced accuracy of method.
机译:领域:医学。物质:该方法涉及在外周血的天然细胞和天然吗啡化的单核细胞中,在吗啡和诺氟沙星的共同作用下,体外测定在测试负荷下的环状腺苷一磷酸浓度。易感指数是通过将天然预形态化细胞中的环腺苷单磷酸浓度除以单核细胞中的值而得出的。该值大于1.3,表示鸦片成瘾的高易感性。效果:提高了方法的准确性。

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