METHOD OF SYNTHESIS OF 1-CHLOROADAMANTANE, 1- AND 4-CHLORODIAMANTANES

摘要

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to a method of synthesis of monochlorosubstituted derivatives of adamantane and diamantane used in production of thermo- and chemostable polymers and as the parent raw used for synthesis of medicinal preparations and in the synthesis of other derivatives of adamantanoids (amines, alcohols, acids). Method is carried out by catalytic chlorination of adamantane and diamantane with carbon tetrachloride. The source of catalyst are manganese salts, for example: MnSO₄,, Mn(C₁₇H₃₅CO₂)₂ (stearate), Mn(OAc)₂, Mn(acac)₃, MnCl₂, activated with nitrile ligands CH₃CN, CH₃CH₂CN,, PhCN, CH₂(CN₂)₂. The mole ratio [Mn] : [RCN] : [adamantane or diamantane] : [CCl₄] = (1:2) - (4:1000) + (1000:5000), respectively. The process is carried out at 200 C for 0.5-8 h. EFFECT: increased conversion of adamantanoids up to 100%. 1 tbl