The use of 1-(2-hydroxyphenyl)-alkan-1-one oxime derivatives (I) for the treatment of erythema formation and/or inflammatory reactions of the skin, is new. The use of 1-(2-hydroxyphenyl)-alkan-1-one oxime derivatives (I) of formula (I) for the prophylaxis of erythema formation and/or inflammatory reactions of the skin is new. Y, Z' = H, 1-18C alkyl, 2-18C alkenyl, 2-18C carboxyalkyl, 3-18C carboxyalkenyl or 2-18C alkanoyl; R = 1-18C alkyl, 2-18C alkenyl, 3-8C cycloalkyl, aryl, heteroaryl, heteroaralkyl or a fused system, and R1-R4 = H, 1-12C alkyl, 2-12C alkenyl, 1-12C alkoxy, 3-8C cycloalkoxy, aryl, aryloxy, heteroaryl, heteroaryloxy, heteroaralkyl, COOH, OH, Cl, dialkylamino or sulfonyl.
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机译:1-(2-羟苯基)-烷-1-酮肟衍生物(I)在治疗红斑形成和/或皮肤炎症反应中的用途是新的。式(I)的1-(2-羟苯基)-烷-1-酮肟衍生物(I)用于预防红斑形成和/或皮肤的炎症反应是新的。 Y,Z′= H,1-18C烷基,2-18C烯基,2-18C羧烷基,3-18C羧烯基或2-18C烷酰基; R = 1-18C烷基,2-18C烯基,3-8C环烷基,芳基,杂芳基,杂芳烷基或稠合系统,R1-R4 = H,1-12C烷基,2-12C烯基,1-12C烷氧基,3 -8C环烷氧基,芳基,芳氧基,杂芳基,杂芳氧基,杂芳烷基,COOH,OH,Cl,二烷基氨基或磺酰基。
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