new mode of administration of hydroxocobalamin and their use in cyanidvergiftungen

摘要

The invention relates to the pharmaceutical field, and more particularly that of therapeutic chemistry. It relates to a new dosage form of hydroxocobalamin which serves in the treatment of cyanide poisoning. The new pharmaceutical compositions according to the invention contain hydroxocobalamin in freeze-dried form. The hydroxocobalamin is freeze-dried in an acidic medium so as to be practically instantly redissolved in a neutral saline solution. The present invention also relates to a process for producing hydroxocobalamin-based pharmaceutical compositions as well as to the first aid kits containing these compositions. Use for the treatment of cyanide poisoning.