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Method of screening substances capable of modifying the activity of a protein or several targets or of a target of a protein expressed in vitro

机译:筛选能够修饰蛋白质或几种靶标或体外表达的蛋白质靶标活性的物质的方法

摘要

Determining the activity of a substance (A) in a functional test (FT) comprising detecting and/or measuring the variation of a known function that corresponds to at least 1 protein (B) in vitro, in presence and absence of (A), or detecting and/or measuring (A), in presence and in absence of (B), is new. Independent claims are also included for the following: (a) a kit for performing the FT; (b) a support for performing the FT comprising a series of locations, each of which allows the detection and/or measurement of a variation of function; and (c) a process for developing new FTs.
机译:确定功能测试(FT)中物质(A)的活性,包括在存在和不存在(A)的情况下在体外检测和/或测量对应于至少一种蛋白质(B)的已知功能的变化,在存在和不存在(B)的情况下检测或测量(A)是新的。还包括以下方面的独立权利要求:(a)执行金融时报的工具包; (b)用于执行FT的支持,包括一系列位置,每个位置都可以检测和/或测量功能的变化; (c)开发新金融时报的过程。

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