New complexes of poly carbon chain anilide derivatives and cyclodextrins, useful for treatment of dyslipidemia, comprise water soluble Acyl Cholesterase Acyl Transferase inhibitors

摘要

Complexes (I), formed between Acyl Cholesterase Acyl Transferase (ACAT) - inhibiting anilide derivatives, comprise a poly carbon chain and cyclodextrins. Complexes (I), formed between Acyl Cholesterase Acyl Transferase (ACAT) - inhibiting anilide derivatives, comprise a poly carbon chain, especially (S)-2'-3'-trimethyl-4'-hydroxy- alpha -dodecyl thio phenyl acetanilide (F12511) and cyclodextrins especially psi -, beta -, and alpha -cyclodextrins or their hydroxypropyl, sulfobutyl ether or methylated derivatives. Independent claims are also included for: (1) Production of (I); and (2) Compositions (II) comprising (I). the production of (I).